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31-Aug-14
Novartis' New Heart Failure Medicine LCZ696 Cuts Cardiovascular Deaths by 20% vs. ACE-Inhibitor in Landmark PARADIGM-HF
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Today at the European Society of Cardiology congress and published simultaneously in the New England Journal of Medicine, Novartis revealed that its investigational heart failure medicine, LCZ696, was superior to ACE-inhibitor enalapril on key endpoints in the largest heart failure study ever done. In PARADIGM-HF patients with heart failure with reduced ejection fraction (HF-REF) who were givenLCZ696 were more likely to be alive and less likely to have been hospitalised for sudden deterioration of their heart failure than those given ACE-inhibitor enalapril. Patients received LCZ696 or enalapril on top of current best treatment.
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